Pleural Mesothelioma
Pleural mesothelioma is the most common form of mesothelioma,
comprising roughly three-quarters of all mesothelioma
cases. It is much more common than peritoneal
mesothelioma, which affects the abdomen. Pleural
mesothelioma affects the pleura, a sheet-like, double-layered
lining attached to the inside of the chest wall and the
outside of the lungs. The space between the two layers
is lubricated with a fluid that circulates within the
lining. This allows smooth movement of the lungs and
other organs in the chest during breathing and general
movement.
When microscopic asbestos fibers enter the lungs through
inhalation, some can eventually become embedded in the
pleural mesothelium. In some people, the asbestos fibers
severely irritate the mesothelial tissue. Eventually,
cancerous tumors and nodules develop in the chest near
or on the pleura. Over time, the layers of the pleura,
which are typically very thin, can begin to thicken.
Pleural effusion, or the accumulation of fluid between
the chest wall and the lungs, almost always develops
in those with pleural mesothelioma. Pain and discomfort
are typically associated with pleural effusion. Severe
pain may be a sign that malignant tumors have spread
into the chest wall, lungs, and surrounding areas.
Symptoms of Pleural Mesothelioma
Symptoms of all forms of mesothelioma typically do not
develop until the disease has reached relatively advanced
stages. The most common symptoms of pleural mesothelioma
are lower-back aches, back and side-chest pain, and difficulty
breathing (dyspnea).
Other symptoms include:
- Shortness of breath
- Trouble swallowing
- Cough
- Hoarseness
- Fever
- Sweating
- Fatigue
- Weight loss
- Swelling of the face and arms
Unfortunately, many of the symptoms of pleural mesothelioma
are similar to those of other diseases, making diagnosis
of this rare disease that much more difficult. If you or
a loved one is experiencing any of the above symptoms -
especially if there is a known history of asbestos exposure
- it is important to see a physician as soon as possible.
Early diagnosis is
one of the most important factors in battling mesothelioma.
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